Organic Chemistry II: With Practical

Author: Dr. Bishwajit Saikia
For B.Sc. 2nd Semester – Major and Minor
As per FYUGP NEP Syllabus

Dibrugarh University and Other Indian Universities

Contents

Chapter 1: Chemistry of Aliphatic Hydrocarbons

1.1 Formation of Alkanes
 1.1.1 Wurtz Reaction
 1.1.2 Wurtz-Fittig Reaction
 1.1.3 Corey-House Reaction

1.2 Free Radical Substitutions: Halogenation
 1.2.1 Chlorination
 1.2.2 Comparison of Halogenation Reactions of Alkanes
 1.2.3 Free Radical Bromination vs Chlorination

1.3 Free Radical Initiators
1.4 Relative Reactivity of Halogens in Alkane Halogenation
1.5 Selectivity of Alkane Halogenation

1.6 Elimination Reactions
 1.6.1 E2 (Bimolecular Elimination) Reaction
 1.6.2 E1 (Unimolecular Elimination) Reaction
 1.6.3 ElcB (Conjugate Base Elimination)

1.7 Saytzeff Eliminations
1.8 Hofmann Elimination

1.9 Special Emphasis on Preparation of Alkenes by Syn Elimination
 1.9.1 Pyrolysis of Esters
 1.9.2 Chugaev Reaction
 1.9.3 Wittig Reaction
 1.9.4 Heck Reaction

1.10 Reactions of Alkenes
1.11 Addition of Halogens to the Double Bond (Trans-addition)
1.12 Stereochemistry of Bromination Reaction
1.13 Addition of Hydrogen Halides (HX)
1.14 Addition of HX to Symmetrical Alkenes
1.15 Addition of HX to Unsymmetrical Alkenes
 1.15.1 Markovnikov Addition
 1.15.2 Anti-Markovnikov Addition (Kharash Effect)

1.16 Oxymercuration-Demercuration
1.17 Hydroboration-Oxidation
1.18 Ozonolysis
1.19 Catalytic Hydrogenation
1.20 Syn and Anti-hydroxylation (Oxidation)
1.21 Woodward and Prevost Dihydroxylation

1.22 1,2- and 1,4-Addition in Conjugated Dienes
1.23 Diels-Alder Reaction
1.24 Endo Rule for Diels-Alder Reaction

1.25 Allylic and Benzylic Bromination
1.26 Stereoselectivity and Stereospecificity

1.27 Acidity of Alkynes
1.28 Electrophilic Addition to Alkynes
1.29 Addition of Halogens
1.30 Addition of Hydrogen Halides (HX)
1.31 Nucleophilic Addition to Alkynes
1.32 Hydration to Form Carbonyl Compounds
1.33 Alkylation of Terminal Alkynes
1.34 Catalytic Reduction
1.35 Chemical Reduction

1.36 Solved Examples

Organic Chemistry Practical

• Experiments aligned with theory topics

• Basic organic lab techniques

• Reactions and identification of functional groups

• Preparation of organic compounds

• Record format and viva guidance